GoldenThread is compatible with all Windows version from XP up to Windows10. ISA does not recommend running it on Vista though because of numerous security hurdles.
We have both 32 and 64 bit versions and recommend having at least 6 Gbytes of RAM on board because images are now becoming larger.
Many users (including ISA) run it on a Mac using either a Fusion or Parallels emulators. While these solutions were clumsy in the past, they are seamless today and work very well, sometimes even better.
GoldenThread software has also been successfully installed on servers for wider institutional access by multiple users.
Please see these suggestions
on one possible approach for doing so. Dongle versions of the software are also available
where the GoldenThread software can installed on multiple platforms but only executed with the USB dongle key installed.